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BETA ARRESTINS
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DeCS
Descriptor
English
:
beta-Arrestins
Descriptor
Spanish
:
beta-Arrestinas
Descriptor
Portuguese
:
beta-Arrestinas
Synonyms
English
:
beta-Arrestin
beta Arrestin
beta Arrestins
Tree Number:
D12.644.360.024.098.525
D12.776.157.057.005.525
D12.776.476.024.104.525
D12.776.543.090.525
Definition
English
:
Non-visual system
arrestins
that negatively regulate G-PROTEIN-COUPLED RECEPTORS (GPCRs) and may also function independently of GPCR signaling. They bind and recruit many different signaling factors, including
MITOGEN-ACTIVATED PROTEIN KINASES
; SRC-FAMILY-KINASES; and FILAMIN to GPCRs and may recognize different
phosphorylation
states of the receptors to determine the specificity of the cellular response to signaling.
History Note
English
:
2017 (1992)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56532
Unique Identifier:
D000071557
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
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